Liga 2 - Meciurile Etapei 18
| Mar 4, 2022 17:30 | Clubul Sportiv al Armatei Steaua | 3 - 1 | ACSM Politehnica Iaşi |  |
| Mar 5, 2022 11:00 | AFC Dunărea 2005 Călăraşi | 0 - 8 | AFC Unirea 04 Slobozia | |
| Mar 5, 2022 11:00 | SC Fotbal Club Ripensia Timișoara | 1 - 0 | AFC 1919 Dacia Unirea Brăila | |
| Mar 5, 2022 11:00 | FC Unirea Dej | 1 - 0 | ACS Viitorul Pandurii Târgu Jiu | |
| Mar 5, 2022 11:00 | Fotbal Club Braşov | 0 - 2 | FC Metaloglobus Bucureşti | |
| Mar 5, 2022 11:00 | AFC Astra | 2 - 3 | AFC Unirea Constanţa | |
| Mar 5, 2022 12:30 | CSC 1599 Şelimbăr | 0 - 3 | AFK Csikszereda Miercurea Ciuc | |
| Mar 5, 2022 17:30 | ACS Petrolul 52 | 0 - 0 | AS Fotbal Club Buzău | |
| Mar 6, 2022 12:30 | CS Concordia Chiajna | 0 - 0 | Politehnica Timișoara | |
| Mar 8, 2022 19:00 | AFC Hermannstadt | 0 - 2 | AS FC Universitatea Cluj | |
* Clubul AFC Astra a fost sancţionat cu o penalitate de 20 puncte prin deciziile CDE din 16.06.2021, 30.06.2021, 07.07.2021, 14.07.2021, 25.08.2021, 22.09.2021, 22.09.2021 şi 28.01.2022
| Loc | Echipa | M | V | E | I | Gol | +/- | Pct |
| 1. | ACS Petrolul 52 | 18 | 15 | 1 | 2 | 38-5 | 33 | 46 |
| 2. | AS FC Universitatea Cluj | 18 | 13 | 0 | 5 | 31-14 | 17 | 39 |
| 3. | AFC Hermannstadt | 18 | 11 | 5 | 2 | 39-14 | 25 | 38 |
| 4. | Clubul Sportiv al Armatei Steaua | 18 | 10 | 4 | 4 | 28-12 | 16 | 34 |
| 5. | CS Concordia Chiajna | 18 | 9 | 6 | 3 | 17-10 | 7 | 33 |
| 6. | AS Fotbal Club Buzău | 18 | 9 | 5 | 4 | 43-13 | 30 | 32 |
| 7. | AFK Csikszereda Miercurea Ciuc | 18 | 10 | 2 | 6 | 31-22 | 9 | 32 |
| 8. | AFC Unirea 04 Slobozia | 18 | 8 | 6 | 4 | 32-13 | 19 | 30 |
| 9. | FC Metaloglobus Bucureşti | 18 | 8 | 4 | 6 | 21-20 | 1 | 28 |
| 10. | SC Fotbal Club Ripensia Timișoara | 18 | 6 | 7 | 5 | 18-18 | 0 | 25 |
| 11. | FC Unirea Dej | 18 | 7 | 4 | 7 | 16-16 | 0 | 25 |
| 12. | CSC 1599 Şelimbăr | 18 | 6 | 5 | 7 | 18-25 | -7 | 23 |
| 13. | ACSM Politehnica Iaşi | 18 | 6 | 4 | 8 | 22-20 | 2 | 22 |
| 14. | ACS Viitorul Pandurii Târgu Jiu | 18 | 5 | 6 | 7 | 15-20 | -5 | 21 |
| 15. | Politehnica Timișoara | 18 | 6 | 3 | 9 | 18-25 | -7 | 21 |
| 16. | Fotbal Club Braşov | 18 | 3 | 4 | 11 | 15-31 | -16 | 13 |
| 17. | AFC Unirea Constanţa | 18 | 3 | 2 | 13 | 16-51 | -35 | 11 |
| 18. | AFC Dunărea 2005 Călăraşi | 18 | 1 | 4 | 13 | 12-47 | -35 | 7 |
| 19. | AFC 1919 Dacia Unirea Brăila | 18 | 0 | 2 | 16 | 7-52 | -45 | 2 |
| 20. | AFC Astra | 18 | 5 | 4 | 9 | 20-29 | -9 | -1 |