Liga 2 - Meciurile Etapei 11
| Oct 21, 2021 19:30 | ACS Petrolul 52 | 2 - 0 | Clubul Sportiv al Armatei Steaua |  |
| Oct 22, 2021 15:30 | AS Fotbal Club Buzău | 1 - 1 | AFC Unirea 04 Slobozia | |
| Oct 23, 2021 11:00 | AFC Astra | 3 - 0 | AFC Dunărea 2005 Călăraşi | |
| Oct 23, 2021 11:00 | AFC Unirea Constanţa | 2 - 0 | AFC 1919 Dacia Unirea Brăila | |
| Oct 23, 2021 11:00 | ACSM Politehnica Iaşi | 1 - 3 | ACS Viitorul Pandurii Târgu Jiu | |
| Oct 23, 2021 11:00 | FC Metaloglobus Bucureşti | 1 - 1 | AFK Csikszereda Miercurea Ciuc | |
| Oct 23, 2021 12:30 | AFC Hermannstadt | 3 - 2 | CSC 1599 Şelimbăr | |
| Oct 23, 2021 15:00 | Politehnica Timișoara | 1 - 3 | SC Fotbal Club Ripensia Timișoara | |
| Oct 24, 2021 12:30 | AS FC Universitatea Cluj | 3 - 1 | FC Unirea Dej | |
| Oct 25, 2021 15:30 | CS Concordia Chiajna | 2 - 1 | Fotbal Club Braşov | |
* Clubul AFC Astra a fost sancţionat cu o penalitate de 20 puncte prin deciziile CDE din 16.06.2021, 30.06.2021, 07.07.2021, 14.07.2021, 25.08.2021, 22.09.2021, 22.09.2021 şi 28.01.2022
| Loc | Echipa | M | V | E | I | Gol | +/- | Pct |
| 1. | ACS Petrolul 52 | 11 | 10 | 0 | 1 | 27-2 | 25 | 30 |
| 2. | AS FC Universitatea Cluj | 11 | 9 | 0 | 2 | 20-7 | 13 | 27 |
| 3. | CS Concordia Chiajna | 11 | 8 | 2 | 1 | 15-4 | 11 | 26 |
| 4. | AFC Hermannstadt | 11 | 7 | 4 | 0 | 25-10 | 15 | 25 |
| 5. | AS Fotbal Club Buzău | 11 | 6 | 3 | 2 | 36-9 | 27 | 21 |
| 6. | Clubul Sportiv al Armatei Steaua | 11 | 6 | 3 | 2 | 17-8 | 9 | 21 |
| 7. | FC Metaloglobus Bucureşti | 11 | 5 | 2 | 4 | 15-16 | -1 | 17 |
| 8. | AFC Unirea 04 Slobozia | 11 | 4 | 4 | 3 | 15-9 | 6 | 16 |
| 9. | CSC 1599 Şelimbăr | 11 | 4 | 2 | 5 | 10-16 | -6 | 14 |
| 10. | SC Fotbal Club Ripensia Timișoara | 11 | 3 | 4 | 4 | 13-16 | -3 | 13 |
| 11. | ACS Viitorul Pandurii Târgu Jiu | 11 | 3 | 4 | 4 | 11-14 | -3 | 13 |
| 12. | AFK Csikszereda Miercurea Ciuc | 11 | 4 | 1 | 6 | 14-19 | -5 | 13 |
| 13. | ACSM Politehnica Iaşi | 11 | 4 | 0 | 7 | 15-15 | 0 | 12 |
| 14. | FC Unirea Dej | 11 | 3 | 3 | 5 | 10-12 | -2 | 12 |
| 15. | Politehnica Timișoara | 11 | 3 | 1 | 7 | 12-18 | -6 | 10 |
| 16. | Fotbal Club Braşov | 11 | 2 | 3 | 6 | 9-21 | -12 | 9 |
| 17. | AFC Unirea Constanţa | 11 | 2 | 1 | 8 | 9-33 | -24 | 7 |
| 18. | AFC Dunărea 2005 Călăraşi | 11 | 0 | 3 | 8 | 8-24 | -16 | 3 |
| 19. | AFC 1919 Dacia Unirea Brăila | 11 | 0 | 2 | 9 | 4-35 | -31 | 2 |
| 20. | AFC Astra | 11 | 4 | 4 | 3 | 13-10 | 3 | -4 |