Liga 2 - Meciurile Etapei 8
| Sep 24, 2021 17:00 | Fotbal Club Braşov | 0 - 1 | Clubul Sportiv al Armatei Steaua |  |
| Sep 25, 2021 11:00 | FC Metaloglobus Bucureşti | 1 - 4 | AFC Unirea Constanţa | |
| Sep 25, 2021 11:00 | AFK Csikszereda Miercurea Ciuc | 2 - 3 | AS Fotbal Club Buzău | |
| Sep 25, 2021 11:00 | AFC 1919 Dacia Unirea Brăila | 0 - 3 | AS FC Universitatea Cluj | |
| Sep 25, 2021 11:00 | CSC 1599 Şelimbăr | 1 - 1 | AFC Astra | |
| Sep 25, 2021 13:00 | FC Unirea Dej | 1 - 3 | ACS Petrolul 52 | |
| Sep 26, 2021 11:00 | ACS Viitorul Pandurii Târgu Jiu | 2 - 1 | Politehnica Timișoara | |
| Sep 26, 2021 11:00 | AFC Unirea 04 Slobozia | 0 - 1 | AFC Hermannstadt | |
| Sep 26, 2021 11:00 | SC Fotbal Club Ripensia Timișoara | 0 - 1 | CS Concordia Chiajna | |
| Sep 28, 2021 17:00 | AFC Dunărea 2005 Călăraşi | 2 - 3 | ACSM Politehnica Iaşi | |
* Clubul AFC Astra a fost sancţionat cu o penalitate de 20 puncte prin deciziile CDE din 16.06.2021, 30.06.2021, 07.07.2021, 14.07.2021, 25.08.2021, 22.09.2021, 22.09.2021 şi 28.01.2022
| Loc | Echipa | M | V | E | I | Gol | +/- | Pct |
| 1. | ACS Petrolul 52 | 8 | 7 | 0 | 1 | 18-2 | 16 | 21 |
| 2. | AFC Hermannstadt | 8 | 6 | 2 | 0 | 19-5 | 14 | 20 |
| 3. | CS Concordia Chiajna | 8 | 6 | 2 | 0 | 12-2 | 10 | 20 |
| 4. | AS FC Universitatea Cluj | 8 | 6 | 0 | 2 | 12-6 | 6 | 18 |
| 5. | Clubul Sportiv al Armatei Steaua | 8 | 5 | 2 | 1 | 13-5 | 8 | 17 |
| 6. | AS Fotbal Club Buzău | 8 | 5 | 1 | 2 | 27-7 | 20 | 16 |
| 7. | AFC Unirea 04 Slobozia | 8 | 3 | 3 | 2 | 13-6 | 7 | 12 |
| 8. | ACSM Politehnica Iaşi | 8 | 4 | 0 | 4 | 13-8 | 5 | 12 |
| 9. | FC Unirea Dej | 8 | 3 | 2 | 3 | 8-7 | 1 | 11 |
| 10. | CSC 1599 Şelimbăr | 8 | 3 | 2 | 3 | 7-10 | -3 | 11 |
| 11. | FC Metaloglobus Bucureşti | 8 | 3 | 1 | 4 | 12-15 | -3 | 10 |
| 12. | SC Fotbal Club Ripensia Timișoara | 8 | 2 | 3 | 3 | 8-10 | -2 | 9 |
| 13. | Fotbal Club Braşov | 8 | 2 | 3 | 3 | 8-13 | -5 | 9 |
| 14. | Politehnica Timișoara | 8 | 2 | 1 | 5 | 9-14 | -5 | 7 |
| 15. | ACS Viitorul Pandurii Târgu Jiu | 8 | 1 | 3 | 4 | 5-11 | -6 | 6 |
| 16. | AFK Csikszereda Miercurea Ciuc | 8 | 2 | 0 | 6 | 8-16 | -8 | 6 |
| 17. | AFC Unirea Constanţa | 8 | 1 | 1 | 6 | 5-29 | -24 | 4 |
| 18. | AFC Dunărea 2005 Călăraşi | 8 | 0 | 3 | 5 | 8-17 | -9 | 3 |
| 19. | AFC 1919 Dacia Unirea Brăila | 8 | 0 | 2 | 6 | 4-24 | -20 | 2 |
| 20. | AFC Astra | 8 | 2 | 3 | 3 | 7-9 | -2 | -11 |